I have been using these strings for roughly 2 years now, in that time i have had my guitar (LTD H351NT) set up in drop A, drop G - but recently I have joined a band that plays in drop A# and C standard.
Used in bedroom jams through basic practise amps, used live through a 6505+ half stack and used in the studio, I have never had any problems with these strings, they never break, but do go a bit dull after maybe 2 months of regular play (of course compared to brand new fresh strings, and i play around 3-7 hours a day, so they get a fair amount of usage)
The only annoying part is that the nut and tuning peg required some filing down as the low string is absolutely massive. (requiring some basic tools and knowledge of how to use them, this process was very basic and only took me 5 minutes with the right tools)
Great strings, dirt cheap, what's not to like?