Great guitar!
I play mostly metal, sometimes punk rock. This guitar handles the styles very well, active pickups provide high gain sounds with great fidelity. I owned several guitars with EMG pickups, I always used to replace EMG 81 in bridge position with EMG 85 due to EMG 81 sounding too harsh and brittle to me. With LTD EC-401 i did not do it for the first time, as EMG 81 sounds just great in bridge position, sound is full a and very harmonic, not harsh in any way. I think this is related to wood of the body (mahogany with no top). I always modify the pickups connection to work in 18 volt mode (two 9 V batteries), which makes the sound more natural and harmonic. This guitar has absolutely best sustain I have ever experienced with any guitar!
The only small complaint about this guitar is instability while playing sitting, guitar body is not very well balanced for that and tends to slip off to the right side, you definitelly need a strap to stabilize the instrument while sitting. However, this is really minor issue and playing while standing is absolutelly comfortable.